Analysis of cytopathologic examination and hybrid capture in women receiving care in basic health units

Authors

  • Deise Jaqueline Ströher
  • Thaís Delgado Brandolt Aramburu
  • Vinícius Tejada Nunes
  • Jacqueline da Costa Escobar Piccoli
  • Vanusa Manfredini

Keywords:

Neoplasm, Papillomaviridae, Molecular biology

Abstract

Introduction: Cervical cancer is one of the most frequent cancers among Brazilian women and its relationship with the human papillomavirus (HPV) is well established. Objective: To analyze the presence of DNA/HPV using Hybrid Capture method for women in the city of Uruguaiana (RS). Methods: During the period of January to December 2015, 51 cervicovaginal samples were collected from patients who sought care at Basic Health Units in the city. After the collection, conventional and liquid-based cytological analysis was performed. Results: The results of the study indicate the prevalence of genital HPV infection in 5.9% of the samples; low-risk DNA/HPV was detected in 3.9% of patients of reproductive age (PIR); and 2.0% of PIR presented highrisk DNA/HPV. By stratifying the prevalence of HPV in age, we found positivity between 16 and 31 years. Conclusion: Conventional cytology is often inconclusive and, in such cases, using molecular biology methods that detect the DNA/HPV presence would be very useful.

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Author Biographies

Deise Jaqueline Ströher

PhD student in the Biochemistry Graduate Program of the Universidade Federal do Pampa – Uruguaiana (RS), Brazil.

Thaís Delgado Brandolt Aramburu

Nurse responsible for the Women’s Health Sector of the Uruguaiana Municipal Health Department – Uruguaiana (RS), Brazil.

Vinícius Tejada Nunes

Nurse from the Universidade Federal do Pampa – Uruguaiana (RS), Brazil.

Jacqueline da Costa Escobar Piccoli

Professor at the Genomics Laboratory of the Universidade Federal do Pampa – Uruguaiana (RS), Brazil.

Vanusa Manfredini

Professor at the Hematology and Cytology Laboratory of the Universidade Federal do Pampa – Uruguaiana (RS), Brazil.

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Published

2016-11-06

How to Cite

1.
Ströher DJ, Aramburu TDB, Nunes VT, Piccoli J da CE, Manfredini V. Analysis of cytopathologic examination and hybrid capture in women receiving care in basic health units. DST [Internet]. 2016 Nov. 6 [cited 2024 Dec. 3];28(4):110-4. Available from: https://bdst.emnuvens.com.br/revista/article/view/775

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Section

Original Article